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Animal drug residue detection instruments can analyze antibiotic residues, hormone residues, and animal diseases in meat products. Applicable to regulatory agencies such as food and drug supervision and management departments, industry and commerce administrative departments, animal husbandry and veterinary, animal health, agriculture and forestry, as well as agricultural product markets, livestock and poultry breeding, and slaughter enterprises.
The animal sample processing process usually includes four basic contents: extraction, purification, concentration, and derivatization. In addition, due to the easy binding or conjugation of drugs with biological matrices such as proteins, many methods require enzymatic hydrolysis steps. The comprehensive influence of various parameters (temperature, pH value, ionic strength, interactions between components, time, concentration, etc.) in each process often cannot be fixed. Therefore, establishing a good pre-treatment method for veterinary drug residue detection requires analysis of various influencing factors.
The selection of solid-phase extraction columns and their extraction steps are crucial sample processing steps in the purification process. The selection of SPE columns based on different mechanisms of action and the establishment of optimized SPE methods are the difficulties and key points in establishing methods for detecting veterinary drug residues. The matrix of animal remains is usually tissue, so a large amount of impurities such as oil and protein need to be removed.